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What can I do to prevent falls? Swimming, cycling and exercising on machines such as elliptical trainers can provide a good cardiovascular workout, but they're not as helpful for improving bone health. Some MEDICINES MAY INTERACT with Fosamax. Fosamax and this debilitating mess I'm in. Joining this site is part of my research. It would be so helpful to find others in similar situations. Those with personal experience know so much more than I could possibly find out in a book, or even perhaps by asking a physician, as specialists can be victims of tunnel vision. I don't expect my family physician to know everything, but more curiosity about my curious situation could have unearthed a lot of this a lot earlier. What I'd like to know is if anyone has similar experiences with the side effects of Fosamax, and how long it took after cessation of Fosamax therapy for the symptoms to go away. I truly appreciate your comments oh. yes, I am taking vitamin D3 and calcium You obviously have a broad view of all this and not just a little medical knowledge. Thank you so much. I'm still seeking answers to the persistence of symptoms after stopping Fosamax, and any other relevant information anyone might have to share.

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National Osteoporosis Foundation NOF. Fosamax tablets alendronate sodium. FDA Med Bull. Avoid any other medications, including calcium supplements or antacids, for 30 minutes after alendronate is administered. 1 112 See Antacids or Mineral Supplements Containing Divalent Cations under Interactions.

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Shane E, Burr D, Ebeling PR et al. Atypical subtrochanteric and diaphyseal femoral fractures: Report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. Ebeling PR. Osteoporosis in men. New insignts into etiology, pathogenesis, prevention and management. Drugs Aging. IU of vitamin D a day is safe for most people.

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Consider other possible causes of osteoporosis before beginning alendronate. Also used for prevention of corticosteroid-induced osteoporosis. This information should not be used to decide whether or not to take Fosamax or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Fosamax. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Fosamax. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Fosamax.



Fosamax dosing information

Gamble, Merck, Roche, and Sanofi are WebMD sponsors. Merck. Fosamax alendronate sodium tablets and oral solution prescribing information. Whitehouse Station, NJ; 2011 Jan. Please refer to the for information on shortages of one or more of these preparations. Best advice - ALWAYS GET A SECOND OPPINION! Some evidence from postmarketing experience and observational studies suggests a possible association between use of oral bisphosphonates and an increased risk of esophageal cancer. 88 100 101 However, because of conflicting data, 101 102 103 additional study needed to confirm such findings. Eli Lilly and Company. Evista raloxifene hydrochloride tablets prescribing information. Lifestyle changes that help promote healthy bones include increasing weight-bearing exercise, stopping smoking, limiting alcohol, and eating well-balanced meals that contain adequate calcium and vitamin D. You may also need to take calcium and vitamin D supplements. Consult your doctor for specific advice. Think about how much calcium and vitamin D you normally get in your diet. Panelists noted that it's difficult to predict which women will benefit from long-term bisphosphonate use. The Fosamax study did find that women's at the time they discontinued the drug was strongly related to their fracture risk over the next five years, Bauer told panel members. Bone density changes so slowly with treatment that the changes are smaller than the measurement error of the machine. In other words, repeat DXA scans cannot distinguish between a real increase in bone density due to treatment or a mere variation in measurement from the machine itself. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Hycodan produces dose-related respiratory depression by directly acting on brain stem respiratory centers. If respiratory depression occurs, it may be antagonized by the use of naloxone hydrochloride and other supportive measures when indicated. If you have any questions about Fosamax Plus D, please talk with your doctor, pharmacist, or other health care provider.



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Are there any alternatives to the primary approach that you're suggesting? Surgery is scary for just about anyone. I do know people who have had this surgery done when things had become unbearable. They always say later that they ought not to have waited so long. What are the doctors saying for a time table for you? Patient Support Program with Pharma Care Specialty Pharmacy 800-238-7828 ext. 58197 distribution system for the 40-mg dosage regimen. Some of these conditions are risk factors for osteonecrosis. No evidence of metabolism of alendronate. Some medical conditions may interact with Fosamax. Green J, Czanner G, Reeves G et al. Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: case-control analysis within a UK primary care cohort. BMJ. Some people using medicines similar to alendronate have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. Fosamax is in a class of drugs that strengthen bone. Bone is in a constant state of remodeling, whereby old bone is removed by cells called osteoclasts, and new bone is laid down by cells called osteoblasts. pyridostigmine



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Gamble Pharmaceuticals. Actonel risedronate sodium tablets prescribing information. Cincinnati, OH; 2008 Apr. Talk to your doctor about the use of weight-bearing exercises to help prevent weak bones. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness; black, tarry, or bloody stools; chest pain; coughing or vomiting blood; difficult or painful swallowing; mouth sores; new, worsening, or persistent heartburn; red, swollen, blistered, or peeling skin; severe bone, muscle, or joint pain especially in the hip, groin, or thigh; severe or persistent sore throat or stomach pain; swelling of the hands, legs, or joints; swelling or pain in the jaw; symptoms of low blood calcium eg, spasms, twitches, or cramps in your muscles; numbness or tingling in your fingers, toes, or around your mouth. About FAERS: The FDA Adverse Event Reporting System FAERS is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. However, he prescribed Fosamax. I purchase it, but before I took any, since I had never heard of Fosamax, I googled it and came to this web-site. I immediately came to the same conclusion others had. I would rather have a broken bone then suffer self-inflicted cronic illness. Next, I needed to get rid of the medication I had just purchased. I would not flush it because our city water is recycled. I did not want to just throw it away in case someone inadvertently got ahold of it. I decided to put it in a plastic baggy and add water then throw away. Imagine my surprise when the instant the water touched the pills they were instantly completely dissolved - instantly a white milky substance! Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. Take Fosamax while you are sitting or standing. Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. It's possible for these fractures to occur in patients who are not taking bisphosphonates, Sandra Kweder, MD, deputy director of the FDA's office of new drugs, said at a news teleconference. Proper dental care is important while you are taking Fosamax. Brush and floss your teeth and visit the dentist regularly. Known risk factors include cancer, chemotherapy, radiation therapy, corticosteroids, poor oral hygiene, preexisting dental disease, anemia, coagulopathy, and infection. Do not lie down for 30 minutes after taking Fosamax Plus D and until you eat your first food of the day. And in studies of up to 10 years of use, Santora said, there were no reports of jawbone death and no difference in the risk of unusual thigh fractures between women who took the drug and those who didn't. Do you think you get enough calcium? The Sedghizadeh study appears in the January issue of the Journal of the American Dental Association. Schmidt GA, Horner KE, McDanel DL et al. Risks and benefits of long-term bisphosphonate therapy. Am J Health Syst Pharm. idiz.info topamax



Indications and usage of fosamax

Wood AJJ. Treatment of postmenopausal osteoporosis. N Engl J Med. But if you are at high risk and cannot take other medicines, your doctor may recommend it under certain circumstances. Tell your doctor or dentist that you take Fosamax before you receive any medical or dental care, emergency care, or surgery. Watts notes that bone-loss drugs should be taken for many years. But most patients stop taking them after six or seven months -- greatly reducing their potential benefit. FOSAMAX 70 mg once weekly and FOSAMAX 10 mg daily. Talk with your doctor before you drink alcohol, smoke, or use other tobacco products while taking Fosamax. My mother had such severe osteoporosis that her bones were down to a lace-like structure by the time she died. She could be sitting still in a chair and have ribs break. She was on morphine so much in the last couple of years that her personality changed. I know first-hand that's not a fate I want to experience, but destroying the current quality of my life to prevent that outcome doesn't make any sense either. Treatment recommendations are often based on an estimate of your risk of breaking a bone in the next 10 years using information such as the bone density test. If the risk is not high, treatment might not include medication and might focus instead on modifying risk factors for bone loss and falls. Forteo is not used to prevent osteoporosis or to treat mild cases. What Are the Side Effects of Forteo? If I hadn't called my family doctor out of frustration, I never would have known to stop taking the medication. Funny thing is, all the doctors I saw had a complete list of my meds but never questioned the possibility of side effects. order prescription butenafine online



Highlights for fosamax

Heaney RP. Bone mass, bone loss, and osteoporosis prophylaxis. Ann Intern Med. Fosamax may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Fosamax with caution. Use Fosamax as directed by your doctor. Check the label on the medicine for exact dosing instructions. Why is there so little data on vitamin D and non-bone diseases? If your symptoms do not improve or if they become worse, check with your doctor. But these events are more common in patients taking bisphosphonates than in patients taking other drugs. Animal reproduction studies have not been conducted with Hycodan. It is also not known whether Hycodan can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Hycodan should be given to a pregnant woman only if clearly needed. Certain fractures of the thigh bone femur have been reported in patients using bisphosphonates. It is unknown if bisphosphonates contributed to the fractures. Contact your doctor right away if you experience hip, thigh, or groin pain. Discuss any questions or concerns with your doctor. No substantial differences in safety and efficacy relative to younger adults, but increased sensitivity cannot be ruled out. Center for Drug Evaluation and Research, Food and Drug Administration.



Use of fosamax

How is your diet, especially dairy intake? Do I need to be screened for osteoporosis? National Institute of Arthritis and Musculoskeletal and Skin Diseases: "Once Is Enough: A Guide to Preventing Future Fractures. Merck. Fosamax alendronate sodium tablets patient information. West Point, PA; 1997 Apr. This drug is available at a higher level co-pay. Swallow Fosamax Plus D whole. Do not break, crush, chew, or suck on the tablet before swallowing. Fosamax Plus D is usually taken 1 time each week. Be sure you understand how to take Fosamax Plus D. Contact your doctor or pharmacist if you have any questions. Sedentary lifestyle. People who spend a lot of time sitting have a higher risk of osteoporosis than do those who are more active. Any weight-bearing exercise and activities that promote balance and good posture are beneficial for your bones, but walking, running, jumping, dancing and weightlifting seem particularly helpful. If you have any questions, ask your doctor or pharmacist. Calcium gluconate and calcium lactate. Tell your doctor if you are before using this medication. Jeal W, Barradell LB, McTavish D. Alendronate: a review of its pharmacological properties and therapeutic efficacy in postmenopausal osteoporosis. Drugs. where can u buy tegretol in canada



Fosamax warnings

National Institute of Dental and Craniofacial Research: "Bisphosphonate-Associated Osteonecrosis of the Jaw: Pathophysiology and Epidemiology. Do not take Fosamax Plus D with mineral water, coffee, tea, or juice. Fosamax for the first time. The women were 65 and older. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Americans to take more than is currently recommended. Ironically, my family doctor immediately told me to stop taking Fosamax. That was last Monday afternoon; I'd already taken my weekly dose that morning. At this point, I am praying that the pain and recurring spasms in my leg will fade or go away. order bactrim kit



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In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask questions during your appointment at any time that you don't understand something. The findings probably can be generalized to weekly dosing of Fosamax, he said, but it's unclear how they relate to other bisphosphonates. Do not suck or chew tablets; potential oropharyngeal irritation. The study by Green and colleagues followed patients for nearly twice as long and had more statistical power than the previously reported study. Girgis CM, Sher D, Seibel MJ. Atypical femoral fractures and bisphosphonate use. N Engl J Med. Because osteoporosis is a chronic condition that requires long-term treatment, it is helpful to have long-term data, Bone explains. An important note: even if bone density deteriorates during treatment, it is quite likely that the patient would have lost even more bone density without treatment. Gertz BJ, Holland SD, Kline WF et al. Clinical pharmacology of alendronate sodium. Osteoporos Int. This medication passes into milk. Consult your doctor before -feeding. Remember that your doctor has prescribed this because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Osteoporosis is essentially the result of an imbalance in the pace of bone breakdown and bone replacement. norfloxacin



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Health Care Financing Administration. Medicare program; medicare coverage of and payment for bone mass measurements. 42 CFR Part 410. Interim rule. Fed Regist. Food and Drug Administration. FDA news release: Possible increased risk of thigh bone fracture with bisphosphonates. Silver Spring, MD; 2010 Oct 13. From FDA web site. What kinds of tests do I need to confirm the diagnosis? They can also be tough on your stomach and cause bleeding if you use them every day. Do not take this medication at bedtime or while you are still in bed. It may not be absorbed and you may have side effects.



Important information

Thacker says. "But if she is, and she's still losing bone mass, we start treatment. It is a long-term commitment. The chances are, you will be on it for a long time. This drug is not recommended for use in children. Studies have shown that many children who took this drug had severe side effects such as vomiting, fever, and flu-like symptoms. It appears that the risk is related to use of bisphosphonates for longer than five years. American College of Obstetricians and Gynecologists. Questions and answers on hormone replacement therapy. Washington, DC; Aug 2002. From the American College of Obstetricians and Gynecologists web site. This product is a combination of two medicines: and . Alendronate works by slowing to help maintain strong bones and reduce the risk of broken bones . It belongs to a class of medications called bisphosphonates. What types of side effects can I expect from treatment? Fosamax years ago for Osteopenia. Bone density exams showed improvement. After being on the drug for over five years studies came out suggesting that taking Fosamax for over five years was not a good idea. My GYN and I decided to take a break. A couple years after that I was struck with a nasty case of Sciatica. NOTHING helped. shots. pills. acupuncture. physical therapy. homeopathy that demonstrates my desperation. For over a year and a half I was bedridden on powerful pain medication trying to keep up with raising my twins who are both neurologically and developmentally "disabled" most of the work is navigating the system and fighting bureaucracies. These two people are amazingly bright, talented and have wonderful hearts. The problem is not they; it's. Do not take this medication at bedtime or before rising for the day. It may not be absorbed and you may have side effects. Vitamin D is very similar to calcitriol. Standing Committee on the Scientific Evaluation of Dietary Reference Intakes of the Food and Nutrition Board, Institute of Medicine, National Academy of Sciences. Dietary reference intakes for calcium, phosphorus, magnesium, vitamin D, and fluoride. Washington, DC: National Academy Press; 1997. Prepublication Copy. Orwoll E, Ettinger M, Weiss S et al. Alendronate for the treatment of osteoporosis in men. N Engl J Med. Alendronate has been used concomitantly with hormone replacement therapy. generic azathioprine otc



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D2, -D3, alfacalcidol is a -soluble vitamin that helps your body absorb and phosphorus. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fosamax while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use Fosamax, check with your doctor. Discuss any possible risks to your baby. If any of these effects persist or worsen, tell your doctor or promptly. Medications, healthy diet and weight-bearing exercise can help prevent bone loss or strengthen already weak bones. This effect helps maintain strong bones and reduce the risk of broken bones . Alendronate belongs to a class of drugs called bisphosphonates. Last March, the FDA announced that it was investigating bisphosphonates. Today's warning is a direct result of this continuing investigation. Hycodan tablets also contain: calcium phosphate dibasic, colloidal silicon dioxide, lactose, magnesium stearate, starch and stearic acid. FDA advisory panel voted today. McClung M, Clemmesen B, Daifotis A et al. Alendronate prevents postmenopausal bone loss in women without osteoporosis: a double-blind, randomized, controlled trial. Ann Intern Med. See Food under Pharmacokinetics. If you miss a dose of Fosamax, do not take it later in the day. Take it the morning after you remember and then go back to your regular dosing schedule. Do not take 2 doses within the same day. Side Effects List Fosamax Tablet side effects by likelihood and severity. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Eastell R. Treatment of postmenopausal osteoporosis. N Engl J Med. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Center for Drug Evaluation and Research, Food and Drug Administration. Update of safety review follow-up to the October 1, 2007 early communication about the ongoing safety review of bisphosphonates. indinavir



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Prescribing information for fosamax


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Calcium is in foods such as milk, cheese, and yogurt. Vegetables like broccoli, kale, and Chinese cabbage have calcium. You can get calcium if you eat the soft edible bones in canned sardines and canned salmon. Foods with added fortified calcium include some cereals, juices, soy drinks, and tofu. The food label will show how much calcium was added. Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. Store at room temperature away from light and moisture. not freeze or store in the bathroom. Keep all away from children and pets. Take each dose with a full glass 6 to 8 ounces of water. Use only plain water not mineral water, coffee, tea, or juice when taking an alendronate tablet.

Is alendronate available as a generic drug?

This drug is available at the lowest co-pay. Keep all medicines away from children and pets. That research failed to find a significant increase in esophageal cancer risk in users of the drugs. Proper dental care is important while you are taking Fosamax Plus D. Brush and floss your teeth and visit the dentist regularly. The condition, sometimes called jawbone death, occurs when bone in the jaw fails to heal after a minor trauma. It results in pain, swelling, infection, and exposed bone.

What is fosamax

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Fosamax is available in a tablet or oral liquid form. Cleveland Clinic: "Temporomandibular Disorders.

Fosamax adult dosage

Some people taking alendronate may have serious jawbone problems. Your doctor should check your mouth before you start this medication. Tell your dentist that you are taking this medication before you have any dental work done. To help prevent jawbone problems, have regular dental exams and learn how to keep your teeth and gums healthy. If you have jaw pain, tell your doctor and dentist right away. Race. You're at greatest risk of osteoporosis if you're white or of Asian descent. Low calcium intake. A lifelong lack of calcium plays a role in the development of osteoporosis. Low calcium intake contributes to diminished bone density, early bone loss and an increased risk of fractures.

Oxford University epidemiologist Jane Green, PhD, who led the latest research, says more study is needed to determine if bisphosphonate use really does increase esophageal cancer risk. Ross PD. Osteoporosis: frequency, consequences, and risk factors. Arch Intern Med. Patients at increased risk of aspiration should not receive alendronate oral solution. Holick said at an online news conference.

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